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What (who) is C-Met - definition
C-Met
MAMMALIAN PROTEIN FOUND IN HOMO SAPIENS
Proto-oncogene proteins c-met; HGFR; C-MET; Hgfr; RCCP2; Rccp2; Met proto-oncogene; Hepatocyte growth factor receptor; MET (gene); MET kinase
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity.
C-Met inhibitor
![[[Tivantinib]] (ARQ197), a c-Met inhibitor](https://commons.wikimedia.org/wiki/Special:FilePath/Tivantinib.svg?width=200 "[[Tivantinib]] (ARQ197), a c-Met inhibitor")
CLASS OF COMPOUNDS
Discovery and development of small molecule c-Met inhibitors; C-Met inhibitors; MET inhibitor
c-Met inhibitors are a class of small molecules that inhibit the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF). These inhibitors may have therapeutic application in the treatment of various types of cancers.
Hail fellow well met
ENGLISH IDIOM
Hail-fellow-well-met
"Hail fellow well met" is a somewhat archaic English idiom used when referring to a person whose behavior is hearty, friendly, and congenial, in the affirmative sense.
Examples of use of C-Met
1. The truth emerged only when Mr C met a man who told him Porter had been infected years before.